Heping Yang Selected Research

Methionine Adenosyltransferase

1/2021	Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans.
11/2020	Reciprocal Regulation Between Forkhead Box M1/NF-κB and Methionine Adenosyltransferase 1A Drives Liver Cancer.
1/2016	Deregulated methionine adenosyltransferase α1, c-Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans(‡).
4/2015	Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
1/2015	S-Adenosylmethionine and methylthioadenosine inhibit β-catenin signaling by multiple mechanisms in liver and colon cancer.
8/2013	Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.
1/2013	MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma.
6/2011	Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells.
12/2010	Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
5/2010	Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Heping Yang Research Topics

Disease

16	Neoplasms (Cancer) 05/2021 - 04/2008
12	Liver Neoplasms (Liver Cancer) 01/2021 - 03/2007
9	Carcinogenesis 01/2021 - 02/2008
9	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2008
7	Cholangiocarcinoma 01/2021 - 07/2011
7	Lung Neoplasms (Lung Cancer) 06/2018 - 08/2005
6	Colonic Neoplasms (Colon Cancer) 04/2015 - 07/2007
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2018 - 12/2009
5	Cholestasis 01/2018 - 03/2009
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2013 - 08/2005
4	Adenocarcinoma of Lung 10/2013 - 06/2008
3	COVID-19 03/2021 - 01/2021
3	Infections 01/2020 - 11/2003
3	Neoplasm Metastasis (Metastasis) 01/2017 - 04/2012
3	Liver Diseases (Liver Disease) 01/2015 - 04/2008
3	Fibrosis (Cirrhosis) 10/2012 - 04/2008
3	Adenocarcinoma 01/2010 - 08/2005
2	Inflammation (Inflammations) 01/2013 - 02/2012
1	Type 2 Diabetes Mellitus (MODY) 03/2021
1	Mouth Neoplasms (Oral Cancer) 12/2019
1	Male Infertility (Male Sterility) 01/2018
1	Pneumonia (Pneumonitis) 12/2017
1	Nausea 12/2017
1	Vomiting 12/2017
1	Neutropenia 12/2017
1	Photosensitivity Disorders (Photodermatitis) 04/2015
1	Colitis-Associated Neoplasms 01/2015
1	Lymphatic Metastasis 10/2013
1	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 10/2012
1	Eczema 04/2012

Drug/Important Bio-Agent (IBA)

13	Methionine AdenosyltransferaseIBA 01/2021 - 07/2007
11	Proteins (Proteins, Gene)FDA Link 11/2020 - 08/2005
6	Small Interfering RNA (siRNA)IBA 02/2018 - 12/2009
5	Messenger RNA (mRNA)IBA 01/2019 - 07/2007
5	S-Adenosylmethionine (Ademetionine)IBA 01/2016 - 07/2007
4	EnzymesIBA 12/2017 - 10/2005
3	ProhibitinsIBA 01/2019 - 12/2010
3	Pemetrexed (MTA)FDA Link 01/2015 - 07/2007
2	NF-kappa B (NF-kB)IBA 11/2020 - 10/2005
2	Pharmaceutical PreparationsIBA 09/2020 - 12/2017
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2019 - 10/2005
2	DNA (Deoxyribonucleic Acid)IBA 06/2018 - 12/2011
2	Cisplatin (Platino)FDA LinkGeneric 02/2018 - 12/2011
2	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2018 - 07/2011
2	Levofloxacin (Levaquin)FDA Link 12/2017 - 01/2012
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 04/2015 - 06/2013
2	MicroRNAs (MicroRNA)IBA 01/2013 - 07/2011
2	Interleukin-6 (Interleukin 6)IBA 01/2013 - 02/2012
2	P-SelectinIBA 10/2012 - 04/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2012 - 10/2005
2	Cyclin D1IBA 07/2011 - 03/2009
2	Glutathione (Reduced Glutathione)IBA 04/2010 - 06/2009
2	LeptinIBA 03/2010 - 02/2008
2	MitogensIBA 07/2007 - 03/2007
1	Metformin (Glucophage)FDA LinkGeneric 03/2021
1	InterferonsIBA 03/2021
1	Ribavirin (Virazole)FDA LinkGeneric 03/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	T0901317IBA 11/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	CarbonIBA 12/2019
1	Interleukin-8 (Interleukin 8)IBA 01/2019
1	MethyltransferasesIBA 06/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 02/2018
1	SurvivinIBA 02/2018
1	Glyphosate (Roundup)IBA 01/2018
1	HerbicidesIBA 01/2018
1	obeticholic acidIBA 01/2018
1	nemonoxacinIBA 12/2017
1	polysialic acidIBA 01/2017
1	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 01/2017
1	Lithocholic AcidIBA 01/2016
1	Maf Transcription FactorsIBA 01/2016
1	VimentinIBA 11/2015
1	Cadherins (E-Cadherin)IBA 11/2015
1	CurcuminIBA 11/2015
1	bisdemethoxycurcuminIBA 11/2015
1	PowdersIBA 04/2015
1	CateninsIBA 01/2015
1	Glycogen Synthase KinasesIBA 01/2015
1	clonidine-displacing substance (ClDS)IBA 01/2015
1	Inflammation MediatorsIBA 01/2015
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 10/2013
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 10/2013
1	Tissue Inhibitor of Metalloproteinase-2IBA 10/2013
1	Tissue Inhibitor of Metalloproteinase-1IBA 10/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2013
1	ResveratrolIBA 08/2013
1	Sirtuin 1IBA 08/2013
1	AntioxidantsIBA 01/2013
1	P-selectin ligand proteinIBA 10/2012
1	N 30IBA 10/2012
1	IntegrinsIBA 04/2012
1	Penicillin G Benzathine (Benzathine Benzylpenicillin)FDA Link 04/2012
1	Betamethasone (Celestone)FDA Link 04/2012

Therapy/Procedure

4	Therapeutics 03/2021 - 04/2012
4	Ligation 01/2018 - 07/2011
2	Immunotherapy 05/2021 - 09/2020
1	Drug Therapy (Chemotherapy) 01/2015
1	Chemoprevention 01/2015